Clinical Coagulation

Clinical Coagulation is the procedure by which blood changes from a liquid to a gel, creating a blood clot. It potentially consequences in haemostasis, the cessation of blood loss from a damaged vessel, followed by repair. The mechanism of coagulation comprises initiation, adhesion, and accumulation of platelets along with deposition and maturation of fibrin. Ailments of coagulation are disease states which consequences in bleeding i.e. haemorrhage or bruising or obstructive clotting also known as thrombosis. Coagulation is highly conserved throughout biology; in all mammals, coagulation comprises of both a cellular and a protein constituent. The system in humans has been the most comprehensively researched and is the best understood.

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