Histocompatibility complex (HLA)

The major histocompatibility complex (MHC) is the cell surface proteins, which are vital for the acquired immune system to identify foreign molecules in vertebrates, which in turn concludes histocompatibility. The chief purpose of MHC molecules is to bind to peptide fragments resulting from pathogens and exhibit them on the cell surface for recognition by the suitable T-cells. A MHC molecule enables the interactions of leukocytes, which are also known as white blood cells (WBCs), these are immune cells, with other leukocytes or with body cells. The MHC defines compatibility of contributors for organ transplant, as well as one's vulnerability to an autoimmune disease via cross reacting immunization. In humans, the MHC is also titled as the human leukocyte antigen (HLA).

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